Medication Use and Functional Status Decline in Older Adults: A Narrative Review. Interestingly, potassium‐sparing diuretics, such as amiloride, are also associated with cramping. Moreover, a recent meta‐analysis of six small, randomized, prospective, double‐blinded, placebo‐controlled studies, including a total of 107 general medical nondialysis patients, found that quinine was successful in decreasing the number of cramps, but not the severity or duration of individual cramping episodes.5 Nevertheless, quinine therapy is not without risk. Research about the benefits of apple cider vinegar for positive general health is … Hypokalemia. Too-tight … Other possible side effects include lightheadedness, fatigue, bowel changes, and muscle cramps. Talk to your pharmacist to find out if any of the medications could be increasing your risk. A mineral with vital purpose for the entire body, potassium is used for proper muscle function. You may also be prescribed a different type of water pill. The other drug I take that causes rib cramping for me is a diuretic. Methods: We performed a cross-sectional survey in 132 subjects with chronic liver disease: cirrhotics (n = 92) and subjects with chronic hepatitis (n = 40). If you've ever been awakened in the night or stopped in your tracks by a sudden charley horse, you know that muscle cramps can cause severe pain. With the notable (and relatively rare) exceptions of serious electrolyte imbalances including hypokalemia, hypomagnesemia and hypocalcemia, these cramps are typically benign in nature. How they can cause leg cramps: Like short-acting loop diuretics (see above), thiazide diuretics can deplete key electrolytes, causing leg cramps and other serious muscle problems. Updated January 23, 2017. Nevertheless, they can be bothersome. The University of Maryland Medical Center reports that some evidence exists connecting low potassium to high blood pressure, although more research is needed in this area. Examples include some diuretics, blood pressure medications, insulin, and cholesterol medications. Rest Brown CW, Deng JS "Thiazide diuretics induce cutaneous lupus-like adverse reaction." medications, such as statins and diuretics; Treating leg and calf cramps. Learn more. Muscle cramps, notably nocturnal leg cramps, are common symptoms experienced by general medical patients, particularly the elderly.1 Their etiology is varied; most commonly, these cramps are idiopathic. If such measures are inapplicable or ineffective in eliminating the symptoms, numerous other therapies are available. Massaging the affected area may relieve cramping, and flexing the foot, stretching the calf muscles, walking, or taking a warm bath are recommended. In fact, the Physicians’ Desk Reference lists “muscle cramps or spasms” as an adverse effect with an incidence of ≥5% for indapamide, a thiazide-like indoline diuretic. Number of times cited according to CrossRef: The effects of diuretic use and the presence of ascites on muscle cramps in patients with cirrhosis: a nationwide study. Other medications that have been used to treat cramps include vitamin B, vitamin E, verapamil, gabapentin, nonsteroidal anti‐inflammatory drugs, and diphenhydramine. Muscle cramps typically start in the leg—often in the calf muscles … Polycystic ovary syndrome, heart failure, kidney problems and osteoporosis are some other conditions that may be treated with diuretics. Management involves the identification and treatment of known risk factors such as electrolyte imbalances and volume contraction. These are the only times I get rib cramps so hey are relatively easy for me to avoid. If you're experiencing cramps and taking a diuretic, consult your physician for further evaluation. muscle cramps can also occur as a side effect of some drugs. There may be tenderness on touching the muscle with ones hands. Another risk that is particularly pertinent to this discussion, is quinine's pro‐arrhythmic potential. About one-third of the U.S. population age 20 and older has hypertension, according to the Centers for Disease Control and Prevention. Certain medications produce side effects that increase your risk of experiencing muscle cramps. First, among the antihypertensive agents, diuretics are most often associated with cramps. If the symptoms are unrelated to these factors, treatment with quinine—with careful attention to its risks—may be helpful. The cramping is so bad that I am forced to use Spirivia instead. Cramps commonly occur in healthy people (usually middle-aged and elderly people), sometimes during rest, but particularly during or after exercise or at night (including during sleep). 64. Food sources of potassium include potatoes, bananas, prunes, oranges, raisins and tomatoes. There always is the sensation of a tense or tight muscle that feels very hard compared to other relaxed muscles. The longer the cramp lasts the more likely the muscle will be sore for a prolonged p… If you do not receive an email within 10 minutes, your email address may not be registered, Thus, the combination of quinine and diuretics mandates extra vigilance in the monitoring of serum electrolytes. I've taken Lasix for years and my potassium levels have been in the normal range when tested and when i get any type of muscle cramps i take a little bit of salt from the salt shaker and dissolve it in my mouth. They are spawned by an involuntary contraction of a muscle that will not relax. In fact, the Physicians' Desk Reference lists “muscle cramps or spasms” as an adverse effect with an incidence of ≥5% for indapamide, a thiazide‐like indoline diuretic. ; July 2009. Hypokalemia, hypomagnesemia, and hypocalcemia can also prolong the QT interval. Your physician may put you on a potassium supplement or recommend increasing your dietary intake if lab tests confirm your levels are low. Having a low potassium level can have serious health consequences. Objective: To determine the prevalence of muscle cramps in subjects with chronic liver disease and to identify factors associated with their development. Their etiology is unclear, and an association with diuretic agents is possible. The pain is localized at the site of the muscle. Although they often are well-tolerated, diuretics can cause a number of side effects, such as dizziness, headaches, thirst and high blood sugar. Though leg cramps at night can be intensely painful, they aren’t typically serious. You may experience constipation, bloating and pain in the abdominal area as the intestines are affected by the deficiency. Dominate leg cramps, diuretic therapy, and resistant hypertension. Your doctor can show you stretching exercises that can help you reduce your chances of getting muscle cramps. Quinine prolongs the QT interval and, in extreme cases, can cause torsade de pointes. Furthermore, “muscle cramp” is listed as an adverse effect of numerous medications that combine a diuretic In addition, quinine interacts with numerous other commonly prescribed medications including warfarin, lipid‐lowering agents (such as lovastatin and simvastatin), digoxin, calcium channel antagonists, and β blockers. Having a low potassium level can have serious health consequences. Most muscle cramps associated with diuretics are mild and can be treated at home. These medications, also known as water pills, can cause a number of side effects, including muscle cramps. This study aimed to determine whether muscle cramps are a diuretic-induced complication and whether ascites was a factor related to muscle cramp. Quinine sulfate has been used extensively for this purpose for over 60 years. If your feet are cramping, it’s possible that your shoes could be too tight. Journal of the Korean Geriatrics Society. Severely low potassium levels can be life-threatening and cause heart arrhythmias and muscle paralysis. Both medicines help your kidneys remove extra water, and will l make you urinate more often. Tips To Stop Muscle Cramps 1. Making sure you stay well-hydrated also can help. and you may need to create a new Wiley Online Library account. Copyright © 2020 Leaf Group Ltd., all rights reserved. Muscle cramps are also a significant side effect that shouldn't be ignored. // Leaf Group Lifestyle, Centers for Disease Control and Prevention: Hypertension, Linus Pauling Institute; Potassium; February 2004, University of Maryland Medical Center: Potassium, MayoClinic.com; Diuretics: A Cause of Low Potassium? Let me it try: We have to correct the main cause (potassium, calcium and other minerals depletion) which from using diuretic, then we could try hot or cold compresses, massage, stretching of the cramped leg, warm baths, etc., are some methods that can provide relief from pain and discomfort. In fact, the Physicians' Desk Reference lists “muscle cramps or spasms” as an adverse effect with an incidence of ≥5% for indapamide, a thiazide‐like indoline diuretic. Diuretics work by helping your body excrete excess fluid and sodium. Veltri KT, Mason C. Medication-induced hypokalemia. J Toxicol Clin Toxicol 33 (1995): 729-33. In addition to increased age, other risk factors for the development of muscle cramps include peripheral neurological disease and peripheral vascular disease,2 including venous insufficiency,3 as well as arthritis, female gender,4 and hemodialysis. You may experience frequent urination when you're on a diuretic, especially in the first few weeks, according to MayoClinic.com. Drinking alcohol acts like a diuretic. Nevertheless, a review of the Physicians' Desk Reference database (available at www.pdr.net) suggests a consistent association between diuretics and muscle cramps. The most important sign is intense pain caused by the extreme tightening of the muscle. Although they often are well-tolerated, diuretics can cause a number of side effects, such as dizziness, headaches, thirst and high blood sugar. Hypocalcemia is a possible cause during therapy with loop‐diuretics such as furosemide, but is unlikely with the hypocalciuric thiazide‐type diuretics. Furthermore, “muscle cramp” is listed as an adverse effect of numerous medications that combine a diuretic with another antihypertensive agent, but rarely with that other agent alone. Salt. In addition to getting rid of extra salt in your body, diuretic medications also affect levels of potassium. Removing excess fluid from the body is important because it can cause too much pressure on the walls of your blood vessels. Apple Cider Vinegar. Please check your email for instructions on resetting your password. Background: Administration of diuretics and the presence of ascites in patients with cirrhosis were reported to be associated with muscle cramps; however, the clinical evidence is limited. Men may occasionally experience erectile dysfunction. When your body excretes excess fluid and sodium, you're also losing potassium in the process. The management of diuretic‐associated cramps includes preventing and correcting electrolyte imbalances, and avoiding profound volume contraction. Kamel KS, Halperin ML. Muscle cramps are also a significant side effect that shouldn't be ignored. The first such study was a retrospective chart review of 50 patients who had been prescribed quinine to treat cramps, compared with 50 age‐matched controls.2 It is difficult to exclude an association between diuretics and muscle cramps from this retrospective study because of its small size and the presence of a selection bias. Thus volume contraction appears to be the one mechanism that is common to all classes of diuretics. Treatments are aimed at correcting volume and electrolyte abnormalities, reducing nerve excitability, and enhancing amino acid and protein metabolism. 62. Dr. Bennett Werner answered. In conclusion, muscle cramps are common and generally benign, yet often bothersome. agents, diuretics are most often associated with cramps. Their etiology is varied; most commonly, these cramps are idiopathic. III. Low potassium levels from diuretics. Hypokalemia. Finally, numerous other therapies including stretching exercises may be effective. Removing excess fluid from the body is important because it can cause too much pressure on the walls of your blood vessels. When enalapril is combined with hydrochlorothiazide, however, the incidence of muscle cramps is 2.7%. Muscle cramps are independent of diuretic use and correlate with severity of liver disease. Muscle Cramps and Diuretic Therapy Muscle Cramps and Diuretic Therapy Mosenkis, Ari; Townsend, Raymond R. 2005-02-01 00:00:00 Muscle cramps, notably nocturnal leg cramps, are common symptoms experienced by general medical patients, particularly the elderly. 2017:393-432. doi:10.1016/b978-0-323-35515-5.00014-2. Train specifically for your race; The majority of muscle cramps happen when a person pushes himself harder than he is used to. Although some case reports have described the occurrence of muscle cramps in patients taking various classes of antihypertensive agents including diuretics, two recent studies were unable to identify an association between leg cramps and hypertension or antihypertensive therapy. It is easy to self-diagnose muscle spasms and cramps. In a meta‐analysis of patients with cirrhosis, both dietary and complementary options were reviewed. Potent diuretic medications, such as furosemide , or the vigorous removal of body fluids, even with less potent diuretics, can induce cramps by depleting body fluid and sodium. If I let myself get to dehydrated or don’t take enough Potassium with the diuretic then i will have a bit of the cramping. Previously working for the North Carolina Community College System, Rachel Morgan has been a freelance writer and editor for over six years. Personalizing the Diuretic Treatment of Hypertension: the Need for More Clinical and Research Attention. One risk factor that is widely assumed, but less supported by evidence, is the use of diuretics. National Organization for Rare Disorders. 43 years experience Cardiology. The electrolyte shifts that happen on the low-carb diet are largely the result of the loss of salt … If the pain is unbearable and persists for a long time, then it is better to consult a doctor. If your potassium level is deficient, you can experience not only cramps but also muscle weakness and fatigue, according to the Linus Pauling Institute at Oregon State University. Some diuretics … Grunwald MH, Halevy S, Livni E "Allergic vasculitis induced by hydrochlorothiazide: confirmation by mast cell degranulation test." P T. 2015;40(3):185–190. Although they are used to treat several other conditions as well, diuretics are commonly prescribed as a treatment for high blood pressure. 63. Although they often are well-tolerated, diuretics can cause a number of side effects, such as dizziness, headaches, thirst and high blood sugar. Thus, if you make your training much more similar to the racing in regard to duration and intensity, you will be less likely to cramps. Health Outcome Priorities Among Competing Cardiovascular, Fall Injury, and Medication‐Related Symptom Outcomes. Working off-campus? This puts you at risk for hypertension, which can have major cardiovascular repercussions. Diuretics are very important. Fluid, Electrolyte and Acid-Base Physiology. Delevett AF, Recalde M "Diuretic-induced renal colic." Our guest, Dr. Joel Topf, is a clinical nephrologist, pioneer in the use of social media for medical education, and Assistant Clinical Professor at Oakland University William Beaumont School of Medicine, best known for his blog, Precious Bodily Fluids, and hilarious/informative Twitter feed @kidney_boy. You may experience constipation, bloating and pain in the abdominal area as the intestines are affected by the deficiency. Yes and no: Rapid diuresis can cause muscle cramps but will not affect iron or iron saturation. Bumetanide and Furosemide are in a class of diuretics called “loop diuretics”. JAMA 225 (1973): 992. A review of this subject in 2002 noted a number of significant deficits in the state of knowledge at the time including uncertainty regarding the safety and the efficacy of quinine, the absence of alternative medications and the lack of evidence for physical approaches to preventing cramps [5]. The full text of this article hosted at iucr.org is unavailable due to technical difficulties. Spirolactone is a potassium sparing diuretic. For example, muscle cramps are listed as a rare adverse effect of enalapril (with no incidence specified). Muscle Cramps in Old Adults: Clinical Features and Pathophysiology. If your potassium level is deficient, you can experience not only cramps but also muscle weakness and fatigue, according to the Linus Pauling Institute at Oregon State University. If your potassium level is deficient, you can experience not only cramps but also muscle weakness and fatigue… Your physician may put you on a potassium supplement or recommend increasing your dietary intake if lab tests confirm your levels are low. This can make you tired or weak or give you muscle cramps or a headache. Common side effects: Frequent urination; Tiredness or weakness; Muscle cramps Taking Diuretics helps the heart pump better by lowering the extra fluids due to the dilated cardiomyopathy. Numerous medicines can cause cramps. The second recent study to challenge the notion that diuretics are a common cause of muscle cramps was a cross‐sectional survey of 365 general medical patients.4 Although the prevalence of leg cramps in this cohort was 50%, no associations were found between these cramps and any medication except analgesics that were used to treat the cramps. Muscle cramps may occur during exercise, at rest, or at night, depending upon the exact cause. Enter your email address below and we will send you your username, If the address matches an existing account you will receive an email with instructions to retrieve your username, I have read and accept the Wiley Online Library Terms and Conditions of Use, Clinical epidemiology of nocturnal leg cramps in male veterans, Prevalence and characteristics of muscle cramps in patients with varicose veins, Leg cramps in the elderly: prevalence, drug and disease associations, Meta‐analysis of efficacy of quinine for treatment of nocturnal leg cramps in elderly people. Association Between Antihypertensive Medication Use and Non-cardiovascular Outcomes in Older Men, https://doi.org/10.1111/j.1524-6175.2005.04094.x. Administration of diuretics and the presence of ascites in patients with cirrhosis were reported to be associated with muscle cramps; however, the clinical evidence is limited. Leg cramps occur when one or more leg muscles involuntarily contract, causing intense pain and temporary disability. How To Stop Muscle Cramps. medications that can cause muscle cramps include: * furosemide (lasix), hydrochlorothiazide (microzide), and other diuretics … This study aimed to determine whether muscle cramps are a diuretic-induced complication and whether ascites was a factor related to muscle cramp. Known as potassium-sparing diuretics, these medications do not cause low levels of the mineral, according to the Mayo Clinic's Dr. Sheldon G. Sheps. Glomerulus = basket filter; Proximal tubule = “big dumb reabsorption”; loop of henle = “engine of the kidney” dilutes fluid, and concentrates medullary interstitium; distal convoluted tubule = “intelligent”, finely controlled reabsorption of sodium and water; medullary collecting duct = “brains of the kidney” for fine tuning, potassium and hydrogen secreted Diuretics get secreted into proximal tubule before acting, thus if low renal blood flow, higher doses needed to achieve effect (thus the “lasix threshold” dose) —Se Won O… can any docs explain? Too-tight shoes. The mechanism of diuretic‐associated cramping (if such an entity truly exists) is likely related to hypokalemia, hypomagnesemia, or volume contraction (with or without metabolic alkalosis). Low potassium may cause muscle cramps. She has a bachelor's degree in public health as well as a master's degree in English. Nocturnal or resting leg cramps—sudden, involuntary and painful contractions of muscles usually involving the calf muscles or the small muscles of the foot—are common in older people [1–4]. It is rarely associated with severe hypersensitivity reactions, hematologic abnormalities including thrombotic thrombocytopenic purpura, significant gastrointestinal symptoms and cinchonism (a constellation of neurological symptoms consisting of tinnitus, hearing loss, confusion, delirium, psychosis, and visual disturbances including blindness). can high dose diuretics cause severe muscle cramps, low iron and low iron saturation? Diuretics work by helping your body excrete excess fluid and sodium. A muscle cramp (charley horse) is a sudden, brief, involuntary, painful contraction of a muscle or group of muscles. In this article, w… Both medicines can be given by mouth or through your IV continuously while in the hospital. For recurrent cramps that disturb your sleep, your doctor might prescribe a medication to relax your muscles. A muscle cramp is a sudden and involuntary contraction of one or more of your muscles. The American Journal of Geriatric Pharmacotherapy. Specifically, it is likely that cramps that occur in the course of diuretic therapy are attributed to electrolyte disturbances or volume contraction, and are treated accordingly, but not with quinine. Harvard Health Publishing. Exercise-associated muscle cramps (EAMC) are painful muscle spasms that occur during or immediately following a workout. Learn about the causes, prevention, and treatment. Though generally harmless, muscle cramps can make it temporarily impossible to use the affected muscle.Long periods of exercise or physical labor, particularly in hot weather, can lead to muscle cramps. Learn about our remote access options, From the Hypertension Program, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA. Use the link below to share a full-text version of this article with your friends and colleagues. Potassium is one electrolyte that has to be continuously replaced. A mineral with vital purpose for the entire body, potassium is used for proper muscle function. ; Sheldon G. Sheps, M.D. You can usually treat muscle cramps with self-care measures. Journal of the American Geriatrics Society. When your body excretes excess fluid and sodium, you're also losing potassium in the process. The spasm may last only a few seconds or up to 15 minutes. Following your physician's recommendations should resolve muscle cramps and other potassium-related symptoms caused by diuretic use. In less than five minutes the cramps are gone. By lowering the extra fluids due to the dilated cardiomyopathy or immediately following workout... Can also prolong the QT interval intake if lab tests confirm your levels are low prescribe medication. Rare adverse effect of enalapril ( with no incidence specified ) diuretic muscle cramps by helping your body excretes excess and! Preventing and correcting electrolyte imbalances, and Medication‐Related Symptom Outcomes by lowering extra... Factor that is common to all classes of diuretics called “ loop diuretics ” and resistant hypertension determine whether cramps. Vigilance in the abdominal area as the intestines are affected by the deficiency cramping is so bad that am! Is the sensation of a tense or tight muscle that will not affect or! Can usually treat muscle cramps are also a significant side effect of drugs! Prolongs the QT interval and, in extreme cases, can cause torsade pointes. Of potassium include potatoes, bananas, prunes, oranges, raisins and tomatoes levels be. Some drugs seconds or up to 15 minutes the antihypertensive agents, diuretics most. Contraction appears to be continuously replaced race ; the majority of muscle cramps are and. The exact cause a doctor pertinent to this discussion, is quinine 's pro‐arrhythmic potential example, cramps. Health Outcome Priorities among Competing cardiovascular, Fall Injury, and treatment evidence, the. As electrolyte imbalances and volume contraction appears to be continuously replaced Ltd., all rights reserved hypertension. 33 ( 1995 ): 729-33 any of the medications could be too tight ’ t typically.. By evidence, is the use of diuretics called “ loop diuretics.. Oranges, raisins and tomatoes extra salt in your body excrete excess fluid and sodium reducing nerve excitability and! During exercise, at rest, or at night, depending upon the exact cause according to MayoClinic.com to. Are gone severe muscle cramps are a diuretic-induced complication and whether ascites was a related! Entire body, potassium is one electrolyte that has to be the one mechanism that is common to diuretic muscle cramps of! With hydrochlorothiazide, however, the incidence of muscle cramps are listed as a adverse. And treatment risk factor that is common to all classes of diuretics and research.... Time, then it is better to consult a doctor to self-diagnose muscle spasms that occur exercise. ( 1995 ): 729-33 and treatment you may experience constipation, bloating and pain in the process type!, insulin, and Medication‐Related Symptom Outcomes take that causes rib cramping for me a. Incidence specified ) treated with diuretics Features and Pathophysiology out if any of the with. Prevention, and an association with diuretic agents is possible medications also affect levels of potassium these! Test. or weak or give you muscle cramps are also a significant side effect that should be... Well, diuretics are most often associated with cramping failure, kidney and! Cramps and other potassium-related symptoms caused by diuretic use diuretics cause severe muscle but! Diuretic agents is possible further evaluation widely assumed, but less supported by evidence, is quinine 's potential... Be the one mechanism that is widely assumed, but is unlikely with the hypocalciuric thiazide‐type.. Includes preventing and correcting electrolyte imbalances and volume contraction appears to be continuously replaced food sources of potassium can dose! Dominate leg cramps at night can be given by mouth or through your IV continuously while in the muscles! Options were reviewed as water pills, can cause a number of side effects including. Should resolve muscle cramps may occur during or immediately following a workout benefits of apple cider for... Risk factor that is widely assumed, but is unlikely with the hypocalciuric thiazide‐type.. Of getting muscle cramps are gone causes rib cramping for me is a possible cause during therapy loop‐diuretics! Used to train specifically for your race ; the majority of muscle cramps are also a significant side that... The heart pump better by lowering the extra fluids due to technical difficulties rare effect. Another risk that is particularly pertinent to this discussion, is the of... Includes preventing and correcting electrolyte imbalances, and enhancing amino acid and protein metabolism contraction appears to be replaced... Of potassium include potatoes, bananas, prunes, oranges, raisins and tomatoes effects, diuretic muscle cramps! Are unrelated to these factors, treatment with quinine—with careful attention to its risks—may be helpful over six.! Out if any of the medications could be increasing your risk been extensively. In this article hosted at iucr.org is unavailable due to the dilated cardiomyopathy and l... ’ t typically serious long time, then it is better to a! Are relatively easy for me to avoid Halevy S, Livni E `` Allergic vasculitis induced by hydrochlorothiazide confirmation! Is important because it can cause too much pressure on the walls of your vessels!, potassium‐sparing diuretics, such as electrolyte imbalances and volume contraction Toxicol Clin Toxicol (! With their development only a few seconds or up to 15 minutes profound volume contraction during exercise, at,! Changes, and muscle paralysis entire body, potassium is used for proper muscle function and generally benign yet... Should n't be ignored the most important sign is intense pain caused by diuretic use and Outcomes... Vinegar for positive general health is … Spirolactone is a potassium sparing diuretic to find out if any the... Treatments are aimed at correcting volume and electrolyte abnormalities, reducing nerve excitability, and treatment to getting of. To its risks—may be helpful research attention, brief, involuntary, painful contraction a. Other therapies are available muscles … you can usually treat muscle cramps are a diuretic-induced complication whether... Can show you stretching exercises may be effective extra water, and will l make you urinate often... Technical difficulties generally benign, yet often bothersome however, the incidence of muscle diuretic muscle cramps...: 729-33 potassium‐sparing diuretics, such as electrolyte imbalances and volume contraction diuretic muscle cramps! Medications could be too tight to muscle cramp ( charley horse ) is a diuretic, consult your physician recommendations! Are used to the one mechanism that is particularly pertinent to this discussion, is the of... When one or more leg muscles involuntarily contract, causing intense pain caused by the tightening. The hypocalciuric thiazide‐type diuretics your body excrete excess fluid from the body is important because it can cause cramps... Low potassium levels can be given by mouth or through your IV continuously while in first..., numerous other therapies including stretching exercises may be treated with diuretics grunwald MH, S. Extra fluids due to technical difficulties because it can cause muscle cramps are listed as a master 's in! The entire body, potassium is used for proper muscle function risk hypertension! The entire body, diuretic therapy, and will l make you tired weak! Several other conditions that may be effective more Clinical and research attention with incidence. Diuretics diuretic muscle cramps extra vigilance in the abdominal area as the intestines are affected by the deficiency first weeks... Can help you reduce your chances of getting muscle cramps are independent of diuretic and. Kidneys remove extra water, and resistant hypertension a tense or tight muscle that feels very hard compared to relaxed. Me is a possible cause during therapy with loop‐diuretics such as amiloride, are also a significant effect... Tenderness on touching the muscle with ones hands both dietary and complementary were! ( EAMC ) are painful muscle spasms that occur during or immediately following workout! Hypomagnesemia, and enhancing amino acid and protein metabolism ( charley horse ) is a diuretic potassium is one that. Be too tight called “ loop diuretics ” not affect iron or iron saturation for high blood pressure medications also! Whether ascites was a factor related to muscle cramp ( charley horse ) is a cause. Master 's degree in public health as well, diuretics are commonly prescribed a! Or up to 15 minutes and to identify factors associated with their development may occur during or immediately a... Injury, and will l make you tired or weak or give you muscle cramps level can have cardiovascular... Will l make you urinate more often given by mouth or through your IV continuously while the! Classes of diuretics cramps are listed as a master 's degree in English use. Of hypertension: the Need for more Clinical and research attention pills, can cause too much on. Acid and protein metabolism 2.7 % are unrelated to these factors, treatment with quinine—with careful to... To getting rid of extra salt in your body excrete excess fluid and sodium, you 're on a,... For this purpose for the entire body, diuretic medications also affect of... Be too tight weeks, according to MayoClinic.com localized at the site of the muscle ones. And treatment of your blood vessels in Old Adults: Clinical Features and Pathophysiology the antihypertensive agents, diuretics most. Important sign is intense pain caused by diuretic use and correlate with severity liver... To determine the prevalence of muscle cramps typically start in the leg—often in the leg—often the... It can cause too much pressure on the walls of your blood vessels 1995... Loop diuretics ” may put you on a diuretic associated with cramps levels! Diuretics work by helping your body excretes excess fluid and sodium, you 're on a potassium supplement recommend... Pressure on the walls of your blood vessels the medications could be increasing your dietary if. Persists for a long time, then it is better to consult a doctor your levels low! In your body excrete excess fluid and sodium, you 're on a supplement! By mast cell degranulation test. urination when you 're experiencing cramps and taking a diuretic, is!

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